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In contrast, a broader approach using chronic administration of sodium bromide, which enhances neuronal hyperpolarization by substituting chloride ions in the GABA-A receptor, was effective across three different genetic mouse models of ASD ( Oprm1 -KO, Fmr1 -KO, and Shank3 ex13-16-/- mice)

[Google Scholar] 39.Vasdev S, Ford CA, Longerich L, Gadag V, Wadhawan S

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These may include: Nausea Vomiting Diarrhea Constipation Bloating Mild fatigue Symptoms are most common when starting therapy or increasing the dose